Flow Hydrogenation of 1,3,5-Trinitrobenzenes over Cu-Based Catalysts as an Efficient Approach for the Preparation of Phloroglucinol Derivatives

Flow Hydrogenation of 1,3,5-Trinitrobenzenes over Cu-Based Catalysts as an Efficient Approach for the Preparation of Phloroglucinol Derivatives Научная публикация

Журнал

Synthesis
ISSN: 0039-7881 , E-ISSN: 1437-210X

Вых. Данные

Год: 2022, Том: 54, Номер: 16, Страницы: 3605-3612 Страниц : 8 DOI: 10.1055/a-1807-3188

Авторы

Nuzhdin Alexey L. ¹ , Shchurova Irina А. ² , Bukhtiyarova Marina V. ¹ , Bulavchenko Olga A. ¹ , Alekseyeva Natalia A. ² , Sysolyatin Sergey V. ² , Bukhtiyarova Galina A. ¹

Организации

1	Boreskov Institute of Catalysis SB RAS, Lavrentieva Ave. 5, Novosibirsk 630090, Russian Federation
2	Institute for Problems of Chemical and Energetic Technologies SB RAS, Sotsialisticheskaja str. 1, Biysk 659322, Russian Federation

An environmentally friendly and safe synthesis of phloroglucinol and its derivatives through the flow hydrogenation of 1,3,5-trinitrobenzenes on heterogeneous copper catalysts is reported. It was found that hydrogenation of 1,3,5-trinitrobenzene, 2,4,6-trinitrotoluene, 2,4,6-trinitroxylene, and 2,4,6-trinitromesitylene in methanol over Cu–Al mixed oxides derived from layered double hydroxides led to selective formation of the corresponding triaminobenzenes, which were isolated from the reaction mixture in the form of double salts with sulfuric acid and were stable in storage. Subsequent hydrolysis in aqueous solution gave the phloroglucinol derivatives in good yields (75–82%).

Nuzhdin A.L. , Shchurova I.А. , Bukhtiyarova M.V. , Bulavchenko O.A. , Alekseyeva N.A. , Sysolyatin S.V. , Bukhtiyarova G.A.
Flow Hydrogenation of 1,3,5-Trinitrobenzenes over Cu-Based Catalysts as an Efficient Approach for the Preparation of Phloroglucinol Derivatives
Synthesis. 2022. V.54. N16. P.3605-3612. DOI: 10.1055/a-1807-3188 WOS Scopus РИНЦ CAPlusCA OpenAlex Sciact

Поступила в редакцию:	2 мар. 2022 г.
Принята к публикации:	23 мар. 2022 г.
Опубликована online:	17 мая 2022 г.
Опубликована в печати:	17 авг. 2022 г.

Web of science:	WOS:000834688900007
Scopus:	2-s2.0-85135875416
РИНЦ:	50300370
Chemical Abstracts:	2022:1397911
Chemical Abstracts (print):	179:218824
OpenAlex:	W4221086100
Sciact:	46229