Реферат: An influence of the nature of aliphatic acid of C2 - C8 on the process of enzymatic esterification of butyl and benzyl alcohols was investigated. The process was carried out in hexane with molar ratio of acid: alcohol 1:2 for butanol and 1:1.1 for benzyl alcohol, at the temperature of reaction mixture of 35 °C. Lipase Lipozyme CALB in various concentrations was used. Process course was analyzed by conversion of the corresponding acid. It is established that the process of enzymatic esterification of aliphatic alcohol substrate (butanol) by the enzyme Lipozyme CALB is more efficient than that of benzyl alcohol, at use of identical acid substrates. It was found the most active donator of acyl group for esterification among studied aliphatic acid was acetic acid. The caprylic (n-octanoic) acid having bigger molecular weight and the weakest acidic properties was the weakest acyl donator, and the process of esterification with this acid runs the least efficiently. Results of experiments have shown that activity of aliphatic acids as acyl-donators in processes of an esterification dependent on nature of alcoholic substrate and is determined both by the steric factor, in this case length of a hydro carbonic chain of acid, and by the acid properties (value of pKa).

Библиографическая ссылка: Gamayurova V.S. , Jamai M. , Chernykh M.N. , Zaripova S.K.
The Influence of Acyl Donators on The Enzymatic Activity of Lipase Lipozyme CalB in The Esterifieation Process
Journal of Advanced Chemical Sciences. 2017. V.3. N1. P.478-479.

Идентификаторы БД: Нет идентификаторов